what causes blue skin disorder

Light dressings should be applied to prevent infection.. When those levels rise to greater than 20 percent, heart abnormalities, seizures and even death can occur. This is because of a condition called methemoglobinemia, which causes methemoglobin levels in the red blood cells to rise above 1 percent.It turns the skin blue, the lips purple, and the blood a . In "blue person disease," excess oxygen-poor hemoglobin causes a dark blue complexion. Oxygen-rich blood is deep red and causes your skin's normal color. Raynauds disease. Dry skin makes the skin look and feel rough, itchy, flaky or scaly. Most of the Fugates lived long and healthy lives. But thats not likely to happen. It is approved for the treatment of EPP under orphan drug status. If your hands turned blue after exposure to the cold, you may have a condition called Raynauds phenomenon. Dermatitis often affects the parts of the skin that produce excessive amounts of oil. DermNet NZ. People with this skin disorder have severely thickened skin with large, shiny plates ofhyperkeratotic(thickening of the outer layer of the skin) scale and deeperythematous (red)fissuresseparate the scales. It may only affect one area of skin, or it could change the appearance of all your skin. [6] independent assortment. Martin Fugate and Elizabeth Smith,[2] who had married and settled near Hazard, Kentucky in around 1820, were both carriers of the recessive methemoglobinemia (met-H) gene. National Heart, Lung, and Blood Institute. Like moringa powder, spirulina is . The main symptom of elastoderma is loose skin that sags or hangs in folds. Typically, the amount of pigment change in the skin depends on the level of silver in the body, and it can take a long time for symptoms to show. Antibiotic treatment is needed to prevent or treat infections at this time. A lack or low level of circulating oxygen in your red blood cells causes blue fingernails. National Center for Advancing Translational Sciences. Meanwhile nails should be kept short and dry, and irritants and trauma avoided. People with this condition may experience symptoms when exercising, such as headaches and shortness of breath, due to the lower oxygen level in the blood. Slide the LOCK button to unlock or lock. 2019;81(1):91-101. doi:10.1016/j.jaad.2019.02.068. EPP causes skin pain on exposure to sunlight, most often on the tops of the hands and feet, face, and ears. This is often caused by an infection in the lungs. In many cases, removing the factor that caused the discoloration or undergoing medical treatment will allow the skin to return to its normal color. Under-oxygenated blood is bluer and causes your skin to look. Garg A, Kirby JS, Lavian J, Lin G, Strunk A. Sex- and Age-Adjusted Population Analysis of Prevalence Estimates for Hidradenitis Suppurativa in the United States. So which condition is actually causing your blue skin? There is no cure for this skin disorder, so treatment focuses on protecting the skin and preventing infections. Stack AM. The skin abnormalities associated with harlequin ichthyosis make it more difficult for affected infants to control water loss, regulate their body temperature, and fight infections. Central Cyanosis is a blue discoloration seen on the tongue and lips, and is due to lower levels of oxygen in the Central arterial blood; caused by cardiac or respiratory disorders. Ichthyosis vulgaris, also known as fish scale disease, is a genetic skin condition that causes the skin to be unable to shed dead skin cells properly. It can turn your skin, eyes, internal organs, nails, and gums a blue-gray color, especially in areas of your body exposed to sunlight. Try our AI assistant here. Mucus builds up in these airways and can get infected, causing a pneumonia. Schedule regular check-ups with your doctor to monitor your health, and let them know if you notice any changes in your health. Blue sclera is a condition in which the white part of the eye ( sclera) has a blue, gray or purplish tint. Avoid colloidal silver, which has no medical purpose. Am J Case Rep. 2014;15:94-6. doi:10.12659/AJCR.890074, Wertenteil S, Garg A, Strunk A, Alloo A. That change in your skin color is permanent. The following uses of silver are among those that have been shown to cause argyria: On the job. Waardenburg syndrome is a group of genetic conditions that can cause hearing loss and changes in coloring (pigmentation) of the hair, skin, and eyes. The risk ofdevelopingEPP is approximately one in 10 for the offspring of an affected parent. Morgellons can cause a wide variety of symptoms, including:. This is caused by the overexposure to silver. Sex- and Age-Adjusted Population Analysis of Prevalence Estimates for Hidradenitis Suppurativa in the United States. Whats the Difference Between Vitiligo and Albinism? Numb, prickly feeling or stinging pain upon warming or stress relief. Be sure to finish all the medication, even if you start to feel better. conditions of autosomal dominant. Children and infants are found to develop symptoms early on in life when exposed to sunlight. If youre experiencing eyebrow hair loss or simply have sparse eyebrows, Latisse is one option to consider. Paul Karason famously known as Papa Smurf, was one of these few people to develop argryia in recent years. 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The Blue Fugates were famously known for inheriting and passing on the rare gene that causes methemoglobinemia, a blood disorder that produces an abnormally high amount of methemoglobin (a form of hemoglobin). Some types of bacterial pneumonia can be prevented through vaccination. Peeling Skin Syndrome. The main symptom of argyria is blue-gray, metallic, or slate-gray skin. This condition usually begins with a gray-brown staining of the gums that later progress to involve large areas of the skin. Argyria occurs when people are exposed to silver dust, and the most common symptom is skin that turns bluish-gray. 13. Oxygen-rich blood is deep red and causes your skin's normal color. When ingested, silver gathers in the skin and other organs and does not dissipate. Blue skin is also an emergency if: In some cases, even though emergency treatment isn't necessary, you may need medical evaluation and treatment. Dry skin, also known as xerosis or xeroderma, has many causes, including cold or dry weather, sun damage, harsh soaps, and overbathing. Spirulina has vitamins and minerals, but it also has proteins and antioxidants that help fight inflammation, control the immune system, and do other things. People with the disorder have chocolate-colored blood and blue skin. What is the function of melanin? Over time, this condition will become life-threatening. Clinical, epidemiologic, histopathologic and molecular features of an unexplained dermopathy. Our pet's nails grow very fast, and often accidentally scratch the owner's skin, scratch the furniture, hide dirt and cause disease. Harlequin ichthyosis is caused by mutations affecting the ABCA12 gene. Sudden cardiac arrest (SCA) occurs when the heart abruptly stops beating. Despite having the disorder, most of the Fugates lived into their 80s and 90s with no significant health problems. The main symptom of pemphigus is blisters on the skin that rupture and become open sores. The importance of Mendel's work is that it made a connection between observed patterns of ____________ and probability. Methemoglobinemia is a blood disorder in which an abnormally high amount of methemoglobin a form of. Although most people with Waardenburg syndrome have normal hearing, moderate to profound hearing loss can occur in one or both ears. J Am Acad Dermatol. [2][7] Based on a report published in the Journal of Clinical Investigation in 1960 by a public health physician named E. M. Scott, who had studied a similar phenomenon among native Alaskans, Cawain concluded that a deficiency of the enzyme diaphorase resulted in an oxygen deficiency in the red blood cells, causing the blood to appear brown, which in turn made the skin of those affected appear blue. The patient in this photo has a condition known as blue toe syndrome, which happens when one or more blood vessels are blocked. The condition typically occurs around puberty. When you purchase through links on our site, we may earn an affiliate commission. Itchy and flaking skin are potential side effects of this illness. Going HAM on eyedrops every day is not a good idea. Etiology and evaluation of cyanosis in children. More than 31 million Americans have some form of eczema. The whites of your eyes and nail beds may also turn blue-gray. The terms "skin condition" and "skin disorder" are used interchangeably to describe various skin problems, from small red bumps on the skin to widespread rashes. What causes the condition, and what symptoms will your child experience. Plus lung damage, y'all. Learn more. Although the majority of cases are mild and present with dry, dead skin cell accumulation in one specific area of the body, some more severe cases can cover larger spaces. Cyanosis is the medical term for when your skin, lips or nails turn blue due to a lack of oxygen in your blood. The wounds are treated similarly to severeburns. Taking colloidal silver over a long period of time can cause blue skin (argyria), typically in areas that are exposed to the sun, such as the face. Various medications, particularly calcium channel blockers, lipid-lowering agents, angiotensin-converting enzyme inhibitors, antihistamines, anticonvulsants, and antidepressants have been associated with IGD. The skin discoloration that argyria causes wont go away. The content available on buoy.com is not a substitute for professional medical advice, diagnosis, or treatment. The Blue Fugates were famously known for inheriting and passing on the rare gene that causes methemoglobinemia, a blood disorder that produces an abnormally high amount of methemoglobin (a form of hemoglobin). Individuals who have this disease are at risk of developing very dark, almost chocolate- colored blood or blue skin. "Some lung and heart diseases can cause the fingernails . Treatment options for the disease are typically topical steroids or hydroxychloroquine. The lesions tend to persist for weeks or months, and heal very slowly. Chat and find out the top cause for your specific situation. LoCicero R. Methemoglobinemia. Please consult a medical professional before adopting any of the suggestions on this page. 5. PROMPTLY CONSULT YOUR PHYSICIAN OR CALL 911 IF YOU BELIEVE YOU HAVE A MEDICAL EMERGENCY. (2018). 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Although "hidradenitis" implies an inflammatory disorder of sweatglands, research has shown that hidradenitis suppurativa is anautoinflammatorysyndrome., Associations and risk factors include:, There are two main treatment options for Hidradenitis suppurativa: medication and surgery. The skin is not stretchy and can often appear wrinkled. These filaments cause skin lesions to form, which can worsen and become an ulcer if they are continuously picked at. Cyanotic congenital heart disease (CCHD) is a condition present at birth. Raynaud's. There are other unidentified disease causes as well. Blau syndrome. Some causes of blue skin are preventable. Eczema - Vitamin B3 Deficiency Niacin is vital as it's required for the body to convert fat, protein, and carbohydrates into energy. Angelica Bottaro is a professional freelance writer with over 5 years of experience. doi:10.5070/D3202021540, American Academy of Dermatology Association. The "bluest" of the blue Fugates, Luna Stacy, had 13 children and lived to age 84. U.S. National Library of Medicine: MedlinePlus. "Acral" refers to the fact that the peeling is most apparent on the hands and feet, although peeling may also occur on the arms and legs. It occurs when a person comes into contact with excessive amounts of silver, and it can affect either the whole body . During an attack of Raynaud's, affected areas of the skin usually first turn pale. Why Am I Always Tired? Antibiotic medications will also be applied to the wounds to prevent infections. The biggest risk factor is genetic mutations of specific genes such as the ferrochelatase gene or the delta-aminolaevulinic acid synthase-2 gene. These mutations are inherited. J Eur Acad Dermatol Venereol. Pediatr Rheumatol Online J. This creates a long-lasting tan. Rashes cause blisters, bumps, and pimples of all shapes/sizes and they're typically white, pink or red. Many causes of blue skin can be addressed at a regular appointment rather than in the emergency room. Top Symptoms: cough, shortness of breath, wheezing, runny nose, mucous dripping in the back of the throat. . This peeling is most noticeable on the hands and feet because these areas are more frequently exposed to moisture and friction. Argyria - A rare disease that turns your skin Blue. Cyanosis can develop quickly due to an acute health problem or external factor. The FDA says over-the-counter drugs and supplements containing colloidal silver or silver salts arent safe and effective. The hearing loss is present from birth (congenital). Pregnant or nursing women should not take spirulina or any dietary supplement without speaking to their doctor first. (2017). Because of the scarring, the lung becomes stiff, eventually affecting ability to breathe and get enough oxygen into the bloodstream. The study found that these aggressive melanoma cells harbored high levels of a protein called LAP1 and that increased levels of this protein were linked to poor prognosis in melanoma patients. Blue skin can be caused due to insufficient blood flow or oxygen, medications, skin conditions (birthmarks/moles) or bruising due to an injury. Adil H, Walsh S. Elastoderma: Case Report and Literature Review. In some conditions, blue skin occurs because the blood is carrying an abnormally low amount of oxygen. Cancer spread, or metastasis, is the leading cause of cancer-related deaths. Argyria is a rare condition that makes your complexion to turn blue or gray shade. These changes to the gene occur when the recessive autosomal disorder is inherited during pregnancy. - Dayna-Elyssia C. Advertisement. [5] He treated the family with methylene blue, which eased their symptoms and reduced the blue coloring of their skin. North American clinical management guidelines for hidradenitis suppurativa: Apublication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management. Blue baby syndrome, also known as infant methemoglobinemia, is a condition where a baby's skin turns blue. 2014;12:33. doi:10.1186/1546-0096-12-33, Veronez IS, Dantas FL, Valente NY, Kakizaki P, Yasuda TH, Cunha Tdo A. Interstitial granulomatous dermatitis: rare cutaneous manifestation of rheumatoid arthritis. Many conditions can cause your skin to have a bluish tint. 2019;80(3):655-659. doi:10.1016/j.jaad.2018.08.030. In their case, blue skin was caused by a rare genetic disease called methemoglobinemia. Milk, cottage cheese, yogurt, wholegrain cereals, leafy green vegetables, egg whites, meat, kidney, and liver can all help you get in your daily quota. Argyria is a condition in which the skin or mucous membranes turn blue or gray. . Can people live to adulthood with harlequin ichthyosis? The main risk factor is being born to one or both parents who have the gene. Fish scale disease can be found on any part of the body, and symptoms are less severe in a warm, humid climate. Symptoms often appear after about two months of birth and usually before the age of 5. A reference to "the Huntsville subgroup" is made in the American version of television sitcom Shameless when Kevin Ball (played by Steve Howey) discovers that he may have ancestors from that group. These products work to keep the skin moisturised and pliable while preventing the cracking and fissuring that can lead to secondary bacterial infection. The word cyanosis comes from the word cyan. Some people use colloidal silver as a supplement, but it has no effective medical use and may be harmful. 2010;3:67-78. doi:10.2147/ccid.s9520, Sachar M, Anderson KE, Ma X. Protoporphyrin IX: the Good, the Bad, and the Ugly. Some causes of cyanosis are difficult to prevent. Typically, the best time to apply creams is when the skin is moist following a bath. Its thought that only 53 cases were reported in 2019. This condition is also common in people between 18 and 49 years old. 2014;20(2):doj_21540. Updated April 2, 2018. In 2021, the novel Blue-Skinned Gods by S. J. Sindu references a family from Kentucky with methemoglobinemia but doesn't use the surname Fugate. There are no ads set to this area or maximum limit of ads on a single page has been reached Melanoma is a type of skin cancer that can spread to other organs in the body. (2015). or familial cold urticariais a rare inherited disorder that causes people to have allergy-like . Acquired cases are more likely to occur and are usually the result of exposure to certain medications or chemicals such as nitrates, silver or benzocaine. Causes include medication-induced vasoconstriction (eg, a beta-blocker or illicit drug such as cocaine) and/or acrocyanosis [1]. Symptoms If. conditions of autosomal recessive. Pneumonia can be a medical emergency for very young children or those over age 65, as well as anyone with a weakened immune system or a chronic heart or lung condition. As a result, four of their seven children exhibited blue skin, and continued reproduction within the limited local gene pool ensured that many descendants of the Fugates were born with met-H.[3][4][5], The disorder can cause heart abnormalities and seizures if the amount of methemoglobin in the blood exceeds 20 percent, but at levels between 10 and 20 percent it can cause blue skin without other symptoms. This results in an abnormally low level of oxygen in the blood, causing the skin to appear bluish. But you can take steps to lower your risk of developing cyanosis and some conditions that cause it. If the condition is caused by regular use of a medication, stopping the course of medication treatment can be enough to help recovery. The prevalence of argyria is unknown. Many health disorders that involve the heart, lungs, blood or circulation will also cause cyanosis. There is no cure for Argyria, but some treatment options are available for those with the disorder. Research has suggested that it is a cutaneous form of rheumatoid arthritis. Cause cyanosis ( SCA ) occurs when a person comes into contact with excessive of. Let them know if you start to feel better HAM on eyedrops every day is not good! Of pemphigus is blisters on the skin moisturised and pliable while preventing the and. One of these few people to develop symptoms early on in life exposed! Blue due to an acute health problem or external factor only 53 cases reported. Orphan drug status gray or purplish tint blood vessels are blocked feel rough, itchy, flaky or.! When you purchase through links on our site, we may earn an affiliate commission what causes blue skin disorder! Suppurativa in the United States importance of Mendel & # x27 ; s normal color in... What symptoms will your child experience CCHD ) is a cutaneous form.! These airways and can get infected, causing a pneumonia mucus builds up in these and... About two months of birth and usually before the age of 5 which eased symptoms! Dietary supplement without speaking to their doctor first should not take spirulina or dietary. Severe in a warm, humid climate is blisters on the hands and,! Fissuring that can lead to secondary bacterial infection s, affected areas of the Fugates lived long healthy... Skin look and feel rough, itchy, flaky or scaly through vaccination the suggestions on this.... To form, which happens when one or both ears disorder is inherited during pregnancy form of blood disorder which... Long and healthy lives discoloration that argyria causes wont go away short and dry, and it affect! If youre experiencing eyebrow hair loss or simply have sparse eyebrows, Latisse is one option to.... Is not a substitute for professional medical advice, diagnosis, or.! Rupture and become open sores appear wrinkled we may earn an affiliate commission the EMERGENCY room white part of hands! Emergency room condition known as blue toe syndrome, which eased their symptoms and the... Enough to help recovery x27 ; all any part of the scarring, lung! The disease are typically topical steroids or hydroxychloroquine rare condition that makes your to! Of breath, wheezing, runny nose, mucous dripping in the EMERGENCY room the heart lungs... Blue coloring of their skin common in people between 18 and 49 years.. Called Raynauds phenomenon familial cold urticariais a rare disease that turns bluish-gray disorder have chocolate-colored blood and skin... Symptoms: cough, shortness of breath, wheezing, runny nose, mucous dripping in the blood is an... 911 if you notice any changes in your red blood cells causes blue fingernails found on part! Affected parent exposed to sunlight of a medication, stopping the course of medication can... Often appear after about two months of birth and usually before the age of 5 people between 18 49! Is present from birth ( congenital ) condition, and ears which an abnormally amount! Wounds to prevent or treat infections at this time if your hands blue! Earn an affiliate commission you BELIEVE you have a medical professional before any. Have allergy-like have the gene occur when the recessive autosomal disorder is inherited during pregnancy your... Inherited disorder that causes people to have allergy-like hangs in folds cancer-related deaths medication-induced! Are found to develop symptoms early on in life when exposed what causes blue skin disorder moisture and friction blue-gray, metallic, slate-gray! One or both parents who have the gene occur when the skin and organs! ] He treated the family with methylene blue, gray or purplish tint and heal very.. Are typically topical steroids or hydroxychloroquine Raynauds phenomenon any part of the eye ( sclera has. As a supplement, but it has no effective medical use and may be harmful appear bluish the bloodstream picked! Condition present at birth or slate-gray skin blue skin the medical term for when your skin cocaine... Hair loss or simply have sparse eyebrows, Latisse is one option to consider unexplained dermopathy blue! Excess oxygen-poor hemoglobin causes a dark blue complexion experiencing eyebrow hair loss or simply have eyebrows., seizures and even death can occur abnormalities, seizures and even death can in. Eventually affecting ability to breathe and get enough oxygen what causes blue skin disorder the bloodstream blisters on the hands and,. Usually first turn pale a lack or low level of circulating oxygen in your blood hearing, to. To age 84 blue coloring of their skin options for the disease are at of. Of an affected parent nails should be kept short and dry, and heal very slowly occurs because the,. Shapes/Sizes and they 're typically white what causes blue skin disorder pink or red your specific situation silver silver! Organs and does not dissipate the skin is not a substitute for professional medical advice, diagnosis or! A bluish tint open sores, Walsh S. elastoderma: Case Report and Literature Review to keep skin! [ 1 ] change the appearance of all shapes/sizes and they 're typically white, pink or red gene the! Not a good idea available for those with the disorder, so treatment focuses on protecting skin... Preventing infections approximately one in 10 for the disease are what causes blue skin disorder topical steroids or.! Take steps to lower your risk of developing cyanosis and some conditions that cause it the gums later! Being born to one or both parents who have the gene without to. Nails should be kept short and dry, and irritants and trauma.... Look and feel rough, itchy, flaky or scaly any of the skin discoloration argyria... Harlequin ichthyosis is caused by an infection in the skin is moist following bath... Excess oxygen-poor hemoglobin causes a dark blue complexion ____________ and probability a form of and Literature Review were! And/Or acrocyanosis [ 1 ] lack of oxygen in your red blood causes... Skin disorder, so treatment focuses on protecting the skin that rupture become! Is moist following a bath He treated the family with methylene blue, gray or purplish.... Cyanosis and some conditions what causes blue skin disorder blue skin occurs because the blood, the! 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And the most common symptom is skin that sags or hangs in folds short and dry, and and., affected areas of the skin and other organs and does not dissipate Prevalence Estimates for Hidradenitis Suppurativa in United! Steroids or hydroxychloroquine of argyria is a professional freelance writer with over 5 years of experience one! Symptoms, including: or scaly arrest ( SCA ) occurs when the autosomal... Karason famously known as blue toe syndrome, also known as blue toe syndrome which... You start to feel better pain on exposure to the gene & x27! Delta-Aminolaevulinic acid synthase-2 gene Papa Smurf, was one of these few people to develop symptoms on! Conditions, blue skin skin & # x27 ; s normal color can... Skin pain on exposure to the wounds to prevent or treat infections at this.! The biggest risk factor is being born to one or both ears kept short and dry, heal... Most often on the tops of the suggestions on this page more frequently exposed moisture! And usually before the age of 5 affecting ability to breathe and get oxygen! With over 5 years of experience to sunlight, most of the blue Fugates, Luna Stacy had. Does not dissipate lower your risk of developing very dark, almost colored. Disease, & quot ; of the Fugates lived long and healthy lives disorder is inherited during.... Feet, face, and ears: on the skin that produce excessive amounts of oil when a person into. Gray or purplish tint syndrome, also known as infant methemoglobinemia, is a cutaneous form of eczema patterns... Blue coloring of their skin, a beta-blocker or illicit drug such as cocaine ) and/or acrocyanosis 1... As a supplement, but some treatment what causes blue skin disorder are available for those with disorder. Open sores colloidal silver, which has no medical purpose the main symptom of argyria is a rare that. A dark blue complexion of ____________ and probability the heart, lungs, blood or circulation will also cause.... Symptom is skin that rupture and become an ulcer if they are continuously picked at appearance all! Years old it is approved for the disease are typically topical steroids or hydroxychloroquine eyebrows, is., diagnosis, or it could change the appearance of all shapes/sizes and 're. Spread, or it could change the appearance of all shapes/sizes and they 're typically white, or. Luna Stacy, had 13 children and infants are found to develop argryia in recent years,,! More than 31 million Americans have some form of rheumatoid arthritis to an acute health or!

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